Showing posts with label Pharma. Show all posts
Showing posts with label Pharma. Show all posts

Wednesday, April 13, 2011

European scientists unveil research to protect water against bioterrorism

EU-funded DINAMICS project presented at inaugural Pharma Test Expo 2011 in Cologne, Germany. Innovations have applications for pharma and food testing

DINAMICS presentation at the Pharma Test Expo

Our drinking water will be safe from potential terrorist attacks thanks to four years of collaborative efforts by European scientists from eight countries working on the DINAMICS research project, visitors to the inaugural Pharma Test Expo 2011 in Cologne, Germany, learned on February 10.

Civilian security became a hot issue of concern following the terrorist attacks on New York’s World Trade Center on September 11, 2001, and the subsequent wave of anthrax letters.

The European Commission responded by co-funding the development of a new water quality warning system to help prevent bioterrorist attacks through its detection of dangerous infectious agents, such as bacteria and viruses.

Scientists representing seven of the 12 leading-edge technology companies and public research institutes involved in the over 7 million-euro DINAMICS project reported on the innovations made since the research began in 2007 at a workshop at the Pharma Test Expo 2011 sponsored by Provenion Engineering, a partner in the DINAMICS project and an exhibitor at the Expo.

Provenion Engineering Stand at the Pharma Test Expo

“The aim of the project is to develop an online monitoring system for detecting the presence of pathogens in drinking water,” said Dr. Sabine Müller, project manager at the German technology transfer center Steinbeis-Europa-Zentrum, which is currently in charge of financial and administrative management of the project as well as knowledge management and dissemination.

The project name, DINAMICS, reveals just how complex the research is. DINAMICS stands for Diagnostic Nanotech & Microtech Sensors.

The DINAMICS consortium brought together experts in the fields of:
  • Water supply Management,
  • Microbiological and molecular biology specimen handling,
  • Nanometric film technology
  • DNA nanostructures
  • Sensor and chip technology (optical and electronics)
  • Microfluidic components (chips)
  • Automated fluid handling
  • Microelectronics and signal processing
  • Scientific instrument engineering
  • Technology transfer
  • Product development

The team produced what Dr Müller called a “lab-on-a-chip platform” to quickly detect pathogens in water. Their prototypes, which should be on the market in several years as both handheld and stationary instruments, include a “cost-effective DNA sensor,” that is combined to microfluidic components and electrical and electronic circuits.

Presentation by Dr. Sabine Müller, Steinbeis-Europa-Zentrum

“These devices are next generation diagnostic tools for our water supply,” said Rolf Boetzel, Sales Manager at Provenion Engineering, the German company that engineered the prototype devices by integrating the various components of the project.

The beauty of the innovation is that it has possible applications in medical diagnostics, the food industry and in pharmaceutical testing, Boetzel added.

To view the DINAMICS workshop presented at the Pharma Test Expo 2011, click here.

For more information on the project, contact:

Dr. Christian Mittermayr, Project coordinator
Lambda GmbH
Tel. +43 7949 2090 3011
E-Mail Mittermayr@lambda.at
www.lambda.at

or

Dr. Sabine Müller
Steinbeis-Europa-Zentrum
Tel. +49 721 9351914
E-Mail: sabine.mueller@steinbeis-europa.de
www.steinbeis-europa.de

or

Rolf Boetzel
Business Development
Provenion GmbH
Tel.:+49 (0)8091-5505-17
E-Mail: r.boetzel@provenion.de
www.provenion.de


You may also want to view the DINAMICS dedicated website:
http://www.dinamics-project.eu/

Thursday, February 10, 2011

Pharma & Biotech Test Expo


One of the pharmaceutical industry's leading authorities on drug substances that could harm our DNA kicked off the workshops at the inaugural Pharma & Biotech Test Expo, now being held in Cologne, Germany.


Dr Andrew Teasdale, chair of AstraZeneca's Genotoxic Impurities Advisory Group, conducted the workshop, "Evaluating the risk of genotoxic impurities", at Koelnmesse on Tuesday, February 8, the opening day of the three-day Pharma & Biotech Test Expo 2011.

Drug manufacturers work continually to ensure their products are free of these toxins.

"Most if not all arise through the synthetic process used to manufacture drugs," said Dr Teasdale, whose groundbreaking book on the subject, Genotoxic Impurities: Strategies for Identification and Control, is due to be published later this month by Wiley.

Regulatory authorities' increasing concern with the potential presence of impurities that are genotoxic in drug products led to the publication of the European Medicines Authority guideline, effective from January 1, 2007, Dr Teasdale said.

The US Federal Drug Administration followed suit with a draft guideline, published in December 2008, but there remain many unanswered questions for regulators and industry.

"The biggest problem area we have is to get a common system," said Dr Teasdale, who gave the example of a drug AstraZeneca produced which the regulators of four different countries queried on 10 issues related to genotoxic impurities. Proof that there is no agreement among the regulators was evidenced by the fact that each highlighted a different area of concern, requiring the company to re-test the drug to answer each of the 10 queries. All tests came back negative, but the major headaches the company endured were unavoidable.

Industry and regulatory authorities will have to work together to achieve a common regulatory approach, he said, though progress is being made, particularly in Europe.

Dr Teasdale is actively involved in the work of the International Committee for Harmonisation to develop a common standard for testing of genotoxic impurities, a process that may take several years.

For the latest news on Pharma Test Expo 2011, visit the website: www.pharmatestexpo.com.


Note: Dr Teasdale's presentation at the Pharma Test Expo 2011 is available to download as a pdf file: 
http://www.hulst-expo.com/downloads/evaluating-gi-risk-pharm-test-expo-workshop.pdf (929kb).

Monday, December 20, 2010

Human.Life.Science.Test Expo comes to Cologne, Germany - Feb 2011

At last, a trade fair that delivers the full portfolio of test technologies, solutions and services specifically for test professionals and technicians working in the life science product development and manufacturing sector.

If you are looking for best of breed testing technologies and leading test service providers and laboratory partners, register here for your ticket to HuLST Expo. Never before has there been an exhibition exclusively focused on test for the Human Life Science Industry.

Medical Device & Technology Test Expo 2011 is the trade show for quality assurance and test professionals working in medical device and technology manufacturing industries. Visitors who have already pre-registered include key quality assurance and test professionals from some of Europe's leading medical device and technology manufacturers, including B. Braun, Medtronic, Philips, and Zimmer, to name but a few.

 
Food & Beverage Test Expo 2011 is the 'must-attend' trade show for quality assurance and test professionals working in Europe's food and drink industry. At both the freely-flowing open forums and the detail-specific workshops, experts will be on hand to provide the answers you need – knowledge that can be implemented in your own laboratory testing and in-line QA testing procedures. 


Pharma Test Expo 2011 is the trade show for Europe's pharmaceutical and bio-pharmaceutical manufacturing industries. Where else can you find all the test and QA solutions you could ever need all under one roof? From applications in early-stage discovery testing of promising entities and subsequent screenings to outsourced CRO testing services and all manner of in-line QA testing – it’s all here.


 
Biotech Test Expo, Here you will find R&D teams, outsourcing managers, analytical/research chemists (organic/inorganic), micro biologists, bio-informatics professionals, regulatory professionals, QA directors and teams, validation professionals and more. For the first time ever, the full range of test and evaluation equipment, together with solutions and service providers, all under one roof. Everything you need for a unique and completely relevant test trade fair.